BDBM50343540 (R)-2-(4-(biphenyl-4-ylmethylamino)-6-chloropyrimidin-2-ylthio)octanoic acid::CHEMBL1774305

SMILES CCCCCC[C@@H](Sc1nc(Cl)cc(NCc2ccc(cc2)-c2ccccc2)n1)C(O)=O

InChI Key InChIKey=FQMPYBCEABTPIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343540   

TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50343540((R)-2-(4-(biphenyl-4-ylmethylamino)-6-chloropyrimi...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed