BDBM50343592 CHEMBL1774529::N-{2-[7-(3-Isopropylphenyl)-1,6-dihydro-2H-indeno[5,4-b]-furan-8-yl]ethyl}acetamide

SMILES CC(C)c1cccc(c1)C1=C(CCNC(C)=O)c2c(C1)ccc1OCCc21

InChI Key InChIKey=VERILOROOMDMCV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343592   

TargetMelatonin receptor type 1A(Human)
The First Affiliated Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50343592(N-{2-[7-(3-Isopropylphenyl)-1,6-dihydro-2H-indeno[...)
Affinity DataKi:  0.0110nMAssay Description:Binding affinity to human MT1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343592(N-{2-[7-(3-Isopropylphenyl)-1,6-dihydro-2H-indeno[...)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT2 receptor expressed on CHO cells microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50343592(N-{2-[7-(3-Isopropylphenyl)-1,6-dihydro-2H-indeno[...)
Affinity DataKi:  13nMAssay Description:Binding affinity to human MT2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMelatonin receptor type 1A(Human)
The First Affiliated Hospital of China Medical University

Curated by ChEMBL
LigandPNGBDBM50343592(N-{2-[7-(3-Isopropylphenyl)-1,6-dihydro-2H-indeno[...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-2-iodomelatonin from human MT1 receptor expressed on CHO cells by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed