BDBM50343674 4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-4-yl)pyrimidin-2-amine::CHEMBL1773334

SMILES O=S(=O)(N1CCNCC1)c1ccc(cc1)-c1ccnc(NC2CCNCC2)n1

InChI Key InChIKey=IXMFEZPRVSMTLE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50343674   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of p38betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50343674(4-(4-(piperazin-1-ylsulfonyl)phenyl)-N-(piperidin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed