BDBM50343764 (S)-1-(4-(7,7-Dimethyl-4-(3-methylmorpholino)-5-oxo-5,7-dihydrofuro[3,4-d]pyrimidin-2-yl)phenyl)-3-ethyl urea::CHEMBL1773085
SMILES CCNC(=O)Nc1ccc(cc1)-c1nc2c(C(=O)OC2(C)C)c(n1)N1CCOC[C@@H]1C
InChI Key InChIKey=YGABZLHQYXEOHY-ZDUSSCGKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50343764
Affinity DataKi: 1.20nMAssay Description:Inhibition of human recombinant mTOR expressed in insect cells using 4E-BP1 substrate after 30 mins by fluorescence resonance energy transfer assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of mTOR in human NCI-PC3 cells assessed as inhibition of p70S6k phosphorylation by electrochemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of mTor in human NCI-PC3 cells assessed as inhibition of Akt phosphorylation at serine473 by electrochemiluminescence assayMore data for this Ligand-Target Pair