BDBM50343988 CHEMBL1779805::N-(2-(5-fluoro-2-(4-fluorophenylthio)benzo[b]thiophen-3-yl)ethyl)propionamide

SMILES CCC(=O)NCCc1c(Sc2ccc(F)cc2)sc2ccc(F)cc12

InChI Key InChIKey=YSLKHVWOBDFWHD-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343988   

TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343988(N-(2-(5-fluoro-2-(4-fluorophenylthio)benzo[b]thiop...)
Affinity DataKi:  4.40nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343988(N-(2-(5-fluoro-2-(4-fluorophenylthio)benzo[b]thiop...)
Affinity DataKi:  226nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343988(N-(2-(5-fluoro-2-(4-fluorophenylthio)benzo[b]thiop...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343988(N-(2-(5-fluoro-2-(4-fluorophenylthio)benzo[b]thiop...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed