BDBM50344126 1-(4-(6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-3-ylamino)piperidin-1-yl)ethanone::CHEMBL1778187

SMILES CC(=O)N1CCC(Nc2[nH]nc3nc(Oc4ccc(F)cc4F)ncc23)CC1

InChI Key InChIKey=ZFUUCXNBMNENRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344126   

TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344126BDBM50344126(1-(4-(6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]py...)
Affinity DataIC50: 690nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed