BDBM50344128 CHEMBL1778185::[6-(2,4-Difluoro-phenoxy)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-(1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-yl)-amine

SMILES Fc1ccc(Oc2ncc3c(NC4CCS(=O)(=O)CC4)[nH]nc3n2)c(F)c1

InChI Key InChIKey=RSNJGADWQQUYPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344128   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344128(CHEMBL1778185 | [6-(2,4-Difluoro-phenoxy)-1H-pyraz...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed