BDBM50344304 2-{1-[(4-Chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid 1-adamantyl ester::CHEMBL1779152

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OC34CC5CC(CC(C5)C3)C4)c2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344304   

TargetProstaglandin G/H synthase 1(Sheep)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50344304(2-{1-[(4-Chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ovine COX1 assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 17 mins by thin-layer chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50344304(2-{1-[(4-Chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mouse COX2 assessed as conversion of [14C]-arachidonic acid to [14C]-prostaglandins preincubated for 17 mins by thin-layer chromatograp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed