BDBM50344361 1-(2,5-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl)urea::CHEMBL1779681

SMILES Oc1ccc2cccc(NC(=O)Nc3cc(Cl)ccc3Cl)c2c1

InChI Key InChIKey=OPWUNYFLYSZYMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344361   

LigandPNGBDBM50344361(1-(2,5-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandPNGBDBM50344361(1-(2,5-dichlorophenyl)-3-(7-hydroxynaphthalen-1-yl...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed