BDBM50344373 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2,3-dibromo-7-hydroxynaphthalen-1-yl)urea::CHEMBL1779842

SMILES Oc1ccc2cc(Br)c(Br)c(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c2c1

InChI Key InChIKey=BNMSZBXOWFIYPX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344373   

LigandPNGBDBM50344373(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2,3-dibr...)
Affinity DataIC50: 7.5nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
LigandPNGBDBM50344373(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(2,3-dibr...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed