BDBM50344480 6-(1-((3R,4R)-3-fluoropiperidin-4-yl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,4-dihydroindeno[1,2-c]pyrazole::CHEMBL1780177

SMILES F[C@@H]1CNCC[C@H]1n1cc(c(n1)-c1ccncc1)-c1ccc-2c(Cc3c[nH]nc-23)c1

InChI Key InChIKey=XMUIHQBLEQJXIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344480   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344480BDBM50344480(6-(1-((3R,4R)-3-fluoropiperidin-4-yl)-3-(pyridin-4...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344480BDBM50344480(6-(1-((3R,4R)-3-fluoropiperidin-4-yl)-3-(pyridin-4...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of B-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed