BDBM50344505 2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3.2.1]octan-3-yloxy)-5-methylpyrimidin-4-yloxy)benzonitrile::CHEMBL1778242

SMILES Cc1c(OC2C[C@@H]3CC[C@@H](C2)N3S(=O)(=O)C2CC2)ncnc1Oc1ccccc1C#N

InChI Key InChIKey=UAAFTIMHEYCTTN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344505   

TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344505(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344505(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  68nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed