BDBM50344876 3-(5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)-1-phenylprop-2-en-1-one::CHEMBL1780081

SMILES FC(F)(F)c1nn(c(c1\C=C\C(=O)c1ccccc1)-c1ccc(Cl)cc1)-c1ccccc1

InChI Key InChIKey=DXUUXOCHRBRBJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344876   

TargetProstaglandin G/H synthase 2(Sheep)
University of Mansoura

Curated by ChEMBL
LigandPNGBDBM50344876(3-(5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Mansoura

Curated by ChEMBL
LigandPNGBDBM50344876(3-(5-(4-Chlorophenyl)-1-phenyl-3-(trifluoromethyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ovine COX1 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed