BDBM50345013 2-(5-(thiazol-2-yl)biphenyl-2-yloxy)acetic acid::CHEMBL1778617

SMILES OC(=O)COc1ccc(cc1-c1ccccc1)-c1nccs1

InChI Key InChIKey=HDZASNXPWCPDLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345013   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50345013(2-(5-(thiazol-2-yl)biphenyl-2-yloxy)acetic acid | ...)
Affinity DataIC50:  1.78E+3nMAssay Description:Displacement of [3H]-PGD2 from CRTh2 receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50345013(2-(5-(thiazol-2-yl)biphenyl-2-yloxy)acetic acid | ...)
Affinity DataIC50:  501nMAssay Description:Antagonist activity at human CRTh2 receptor expressed in HEK cells assessed as inhibition of PGD2-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed