BDBM50345528 CHEMBL1784368::rac-N-(1-(4-(4-fluorophenyl)piperazin-1-ylsulfonyl)propan-2-yl)-N-hydroxyformamide

SMILES CC(CS(=O)(=O)N1CCN(CC1)c1ccc(F)cc1)N(O)C=O

InChI Key InChIKey=MESQXIKYNYUZRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50345528   

TargetCollagenase 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50345528(rac-N-(1-(4-(4-fluorophenyl)piperazin-1-ylsulfonyl...)
Affinity DataIC50: 154nMAssay Description:Inhibition of recombinant human MMP-13 assessed as substrate cleavage after 20 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50345528(rac-N-(1-(4-(4-fluorophenyl)piperazin-1-ylsulfonyl...)
Affinity DataIC50: 226nMAssay Description:Inhibition of recombinant human MMP-14 assessed as substrate cleavage after 20 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50345528(rac-N-(1-(4-(4-fluorophenyl)piperazin-1-ylsulfonyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50345528(rac-N-(1-(4-(4-fluorophenyl)piperazin-1-ylsulfonyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MMP-1 assessed as substrate cleavage after 20 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed