BDBM50345530 CHEMBL1784355::N-(1-((4-(4-fluorophenyl)piperazin-1-ylsulfonyl)methyl)cyclobutyl)-N-hydroxyformamide

SMILES ON(C=O)C1(CS(=O)(=O)N2CCN(CC2)c2ccc(F)cc2)CCC1

InChI Key InChIKey=OGLLJVIOQHNPQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345530   

LigandPNGBDBM50345530(N-(1-((4-(4-fluorophenyl)piperazin-1-ylsulfonyl)me...)
Affinity DataIC50: 91nMAssay Description:Inhibition of ADAMTS-4 assessed as substrate cleavage after 16 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50345530(N-(1-((4-(4-fluorophenyl)piperazin-1-ylsulfonyl)me...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed