BDBM50345991 2-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic acid methyl ester::CHEMBL1783631

SMILES COC(=O)c1ccccc1CNc1ccc(NC(=O)Nc2ccccc2)cc1

InChI Key InChIKey=SJEBDXMGQSTSRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345991   

TargetHypoxia-inducible factor 1-alpha(Human)
Gakushuin University

Curated by ChEMBL
LigandPNGBDBM50345991(2-{[4-(3-Phenylureido)phenylamino]methyl}-benzoic ...)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha transcriptional activity in HEK293 cells incubated for 16 hrs by hypoxia response element-driven luciferase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed