BDBM50346126 CHEMBL1782311::N-Adamantan-1-yl-2-[3-cyano-4-(4-fluoro-phenyl)-6-phenyl-pyridin-2-ylsulfanyl]-acetamide

SMILES Fc1ccc(cc1)-c1cc(nc(SCC(=O)NC23CC4CC(CC(C4)C2)C3)c1C#N)-c1ccccc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346126   

TargetBeta-secretase 1(Human)
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346126(N-Adamantan-1-yl-2-[3-cyano-4-(4-fluoro-phenyl)-6-...)
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed