BDBM50346127 2-(3-cyano-6-(4-fluorophenyl)-4-phenylpyridin-2-ylthio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide::CHEMBL1504056

SMILES CCc1nnc(NC(=O)CSc2nc(cc(-c3ccccc3)c2C#N)-c2ccc(F)cc2)s1

InChI Key InChIKey=LGBTZTVEMHLZST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346127   

TargetBeta-secretase 1(Human)
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346127(2-(3-cyano-6-(4-fluorophenyl)-4-phenylpyridin-2-yl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed