BDBM50346136 2-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-ylamino)-2-oxoethyl 2-(4,6-diphenylpyrimidin-2-ylthio)acetate::CHEMBL1782320

SMILES O=C(COC(=O)CSc1nc(cc(n1)-c1ccccc1)-c1ccccc1)Nc1sc2CCCCc2c1C#N

InChI Key InChIKey=UVOFFIFUGBNYOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346136   

TargetBeta-secretase 1(Human)
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346136(2-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl...)
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed