BDBM50346137 CHEMBL1782321::N1,N6-bis(3-cyano-4,5,6,7,8,9-hexahydrocycloocta[b]thiophen-2-yl)-2,2,3,3,4,4,5,5-octafluorohexanediamide

SMILES FC(F)(C(=O)Nc1sc2CCCCCCc2c1C#N)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1sc2CCCCCCc2c1C#N

InChI Key InChIKey=XTZIDZWATABSGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346137   

TargetBeta-secretase 1(Human)
Singapore Polytechnic

Curated by ChEMBL
LigandPNGBDBM50346137(N1,N6-bis(3-cyano-4,5,6,7,8,9-hexahydrocycloocta[b...)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of BACE1 using peptide substrate Rh-EVNLDAEFKQuencher by fluorescence resonance energy transfer (FRET) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed