BDBM50346208 (1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethyl)phenyl)methanone::CHEMBL1783889
SMILES CC(C)N1CCN(CC1)C(=O)c1ccc(CN2CCCCC2)cc1
InChI Key InChIKey=DSNALXIKDKGHLJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50346208
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat cortical hemispheresMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Janssen Pharmaceutical Companies Of Johnson & Johnson
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3H]-astemizole from human ERG expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKd: 1.82nMAssay Description:Antagonist activity at histamine H3 receptor in rat cortical hemispheres assessed as inhibition of forskolin stimulated cAMP accumulation after 6 hrsMore data for this Ligand-Target Pair