BDBM50346417 6-chloro-2-methoxy-N-(3-(((1R,9aR)-octahydro-1H-quinolizin-1-yl)methylthio)propyl)acridin-9-amine::CHEMBL1782743

SMILES COc1ccc2nc3cc(Cl)ccc3c(NCCCSC[C@@H]3CCCN4CCCC[C@H]34)c2c1

InChI Key InChIKey=HMKAKDYSOOVYMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346417   

TargetAcetylcholinesterase(Bovine)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50346417(6-chloro-2-methoxy-N-(3-(((1R,9aR)-octahydro-1H-qu...)
Affinity DataIC50: 220nMAssay Description:Inhibition of bovine erythrocyte AChE using acetylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50346417(6-chloro-2-methoxy-N-(3-(((1R,9aR)-octahydro-1H-qu...)
Affinity DataIC50: 690nMAssay Description:Inhibition of Equine serum BChE using butyrylthiocholine iodide as a substrate after 20 mins by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed