BDBM50347708 CHEMBL1802462

SMILES Oc1ccc(\C=C2/CN(Cc3ccc(Cl)cc3)C\C(=C/c3ccc(O)c(Br)c3)C2=O)cc1Br

InChI Key InChIKey=RADKNBVRRFNZJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347708   

TargetHistone-arginine methyltransferase CARM1(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50347708(CHEMBL1802462)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of CARM1-mediated methylation of PABP1 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD7(Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50347708(CHEMBL1802462)
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibition of SET7-mediated methylation of histone H3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Human)
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50347708(CHEMBL1802462)
Affinity DataIC50: 6.67E+5nMAssay Description:Inhibition of PRMT1-mediated methylation of NPL3 after 90 mins by scintillation counting in presence of S-adenosyl-l-[methyl-3H]methionineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed