BDBM50347863 CHEMBL1802870

SMILES CCc1nc(C)c(C=C2C(=O)Nc3ccc(NC(=O)C#C)cc23)[nH]1

InChI Key InChIKey=ORKOHXAJFGRZCL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50347863   

TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50347863(CHEMBL1802870)
Affinity DataIC50: 770nMAssay Description:Inhibition of NEK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50347863(CHEMBL1802870)
Affinity DataIC50: 770nMAssay Description:Inhibition of human Nek2 in using [gamma-32P] ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50347863(CHEMBL1802870)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of hemagglutinin epitope-tagged human Nek2 transfected tetracycline-induced in human HEK293 cells pre-incubated for 45 mins by immunopreci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50347863(CHEMBL1802870)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Cdk1/cyclinB using histone H1 as a substrate and [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50347863(CHEMBL1802870)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Plk1 using dephosphorylated alpha-casein as a substrate and [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed