BDBM50348388 CHEMBL1800241

SMILES CC(=O)Nc1ccc(cc1)C(=O)CSc1nc(C)cc(=O)[nH]1

InChI Key InChIKey=NZVOKXQPGIDGBV-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50348388   

TargetHistone deacetylase 6(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant HDAC6 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of recombinant HDAC3 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of recombinant HDAC1 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of recombinant HDAC2 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of recombinant HDAC8 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of recombinant HDAC7 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.79E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 2.79E+4nMAssay Description:Inhibition of recombinant HDAC5 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Universite de Poitiers

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 3.25E+4nMAssay Description:Inhibition of recombinant HDAC4 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of recombinant HDAC9 assessed as inhibition of fluorogenic aminocoumarin release from substrate by trypsin-coupled biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Broad Institute of Harvard and Mit

Curated by ChEMBL
LigandPNGBDBM50348388(CHEMBL1800241)
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed