BDBM50348442 CHEMBL1800948

SMILES NC1=NC2(CCCCC2)N(OCCCOc2ccc(Cl)cc2)C(N)=N1

InChI Key InChIKey=GRBRQDFTCGJVHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348442   

TargetDihydrofolate reductase(Bovine)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50348442(CHEMBL1800948)
Affinity DataIC50: 13.8nMAssay Description:Inhibition of bovine liver DHFR using dihydrofolic acid substrate by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Shanghai Institute of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50348442(CHEMBL1800948)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured every 5 sec over 6 mins in presence of NADPH by UV-Visible spectrophotometric me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed