BDBM50348747 CHEMBL1801059

SMILES O=c1cc(Cn2c(C3CC(F)(F)C3)nc3nccnc32)c2ccc(F)c(F)c2[nH]1

InChI Key InChIKey=ACDZDYRBTXIKDM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50348747   

TargetNitric oxide synthase, inducible(Human)
Kalypsys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50348747BDBM50348747(CHEMBL1801059)
Affinity DataEC50:  120nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Kalypsys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50348747BDBM50348747(CHEMBL1801059)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Kalypsys

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50348747BDBM50348747(CHEMBL1801059)
Affinity DataEC50:  9.20E+3nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as inhibition A23187 induced nitric oxide production incubated for 24 hrs measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed