BDBM50349000 CHEMBL1807385

SMILES COCCCOc1cc(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)Cn2ccnn2)C(C)C)ccc1OC

InChI Key InChIKey=PVITWYQMLYZTLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349000   

TargetRenin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50349000(CHEMBL1807385)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of renin measured every 30 secs for 15 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetRenin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50349000(CHEMBL1807385)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant renin preincubated for 30 mins followed by substrate addition measured after 15 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed