BDBM50349017 CHEMBL1807485

SMILES CCCCS(=O)(=O)Nc1cccc(c1)-c1cc(Nc2cc(nc(C)n2)N2CCN(C)CC2)[nH]n1

InChI Key InChIKey=WBYNEGUTLZQEPR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50349017   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50349017(CHEMBL1807485)
Affinity DataIC50: 110nMAssay Description:Inhibition of GST-tagged FLT3 expressing wild type kinase domain expressed in Sf9 insect cells after 4 hrs by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50349017(CHEMBL1807485)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant GST-tagged Aurora A expressed in Sf9 insect cells after 90 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50349017(CHEMBL1807485)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant GST-tagged VEGFR1 expressed in Sf9 insect cells after 120 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50349017(CHEMBL1807485)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of recombinant GST-tagged VEGFR2 expressed in Sf9 insect cells after 120 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed