BDBM50349023 CHEMBL1807480

SMILES O=C(Nc1cc(n[nH]1)-c1cccc(NS(=O)(=O)c2ccccc2)c1)c1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=PTGDNBWLPMBSTB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349023   

TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50349023(CHEMBL1807480)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant GST-tagged Aurora A expressed in Sf9 insect cells after 90 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50349023(CHEMBL1807480)
Affinity DataIC50: 350nMAssay Description:Inhibition of GST-tagged FLT3 expressing wild type kinase domain expressed in Sf9 insect cells after 4 hrs by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50349023(CHEMBL1807480)
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant GST-tagged VEGFR2 expressed in Sf9 insect cells after 120 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed