BDBM50349027 CHEMBL1807466

SMILES CN1CCN(c2ccc(C(=O)Nc3cc(-c4ccc(NS(=O)(=O)c5ccccc5)cc4)n[nH]3)cc2)CC1

InChI Key InChIKey=TWLIQGHEQROHMD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50349027   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349027BDBM50349027(CHEMBL1807466)
Affinity DataIC50: 590nMAssay Description:Inhibition of GST-tagged FLT3 expressing wild type kinase domain expressed in Sf9 insect cells after 4 hrs by Kinase-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349027BDBM50349027(CHEMBL1807466)
Affinity DataIC50: 590nMAssay Description:Inhibition of wild type FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349027BDBM50349027(CHEMBL1807466)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349027BDBM50349027(CHEMBL1807466)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349027BDBM50349027(CHEMBL1807466)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed