BDBM50349107 CHEMBL1808335

SMILES Cn1nc(C(=O)NCCc2ccccc2)c2CCc3cnc(Nc4ccccc4)nc3-c12

InChI Key InChIKey=AOWRNBGAGSLHKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50349107   

TargetAurora kinase A(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50349107(CHEMBL1808335)
Affinity DataIC50: 677nMAssay Description:Inhibition of Aur-A assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50349107(CHEMBL1808335)
Affinity DataIC50: 697nMAssay Description:Inhibition of CDK2/Cyclin A assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50349107(CHEMBL1808335)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 assessed as [33P]-gamma-ATP incorporation into substrate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50349107(CHEMBL1808335)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of MPS1 assessed as [33P]-gamma-ATP incorporation into substrate P38-betatide by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed