BDBM50349212 CHEMBL1807701

SMILES C[C@@H]1CC[C@H](NC(=O)[C@H](CC2(C)CCCCC2)NC(=O)N2CCOCC2)C(=O)CN1S(=O)(=O)c1ccccn1

InChI Key InChIKey=WYBFWCUCYMPPNV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349212   

TargetProcathepsin L(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50349212(CHEMBL1807701)
Affinity DataIC50: 48.7nMAssay Description:Inhibition of human recombinant cathepsin L using Z-LR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50349212(CHEMBL1807701)
Affinity DataIC50: 136nMAssay Description:Inhibition of human recombinant cathepsin K using z-LR-AFC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCathepsin S(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50349212(CHEMBL1807701)
Affinity DataIC50: 570nMAssay Description:Inhibition of cathepsin S in human Raji cells assessed as decrease in cell surface expression of MHC class 2/CLIP by flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed