BDBM50349687 CHEMBL1809044

SMILES COc1cc(ccc1Nc1ncc(Cl)c(n1)-c1cnc2ccccn12)N1CCN(CC1)C(C)=O

InChI Key InChIKey=ZNLCRBCFRLCIFE-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50349687   

TargetInsulin receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 9nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 9nMAssay Description:Inhibition of auto-phosphorylation of IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 10nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 12nMAssay Description:Inhibition of insulin-induced autophosphorylation of human insulin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 17nMAssay Description:Inhibition of IGF1-induced autophosphorylation of human recombinant IGF1R expressed in mouse fibroblasts by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 17nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349687(CHEMBL1809044)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed