BDBM50349695 CHEMBL1809052

SMILES COc1cc(OC2CNC2)ccc1Nc1ncc(Cl)c(n1)-c1cnc2ccccn12

InChI Key InChIKey=VUOFCNLYVCPXKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349695   

TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349695(CHEMBL1809052)
Affinity DataIC50: 26nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349695(CHEMBL1809052)
Affinity DataIC50: 57nMAssay Description:Inhibition of auto-phosphorylation of IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349695(CHEMBL1809052)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed