BDBM50349697 CHEMBL1809066

SMILES COC(=O)N1CCN(CC1)c1ccc(Nc2ncc(Cl)c(n2)-c2cnc3ccccn23)c(OC)c1

InChI Key InChIKey=ITFHIAOKCYYBNR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349697   

TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349697(CHEMBL1809066)
Affinity DataIC50: 27nMAssay Description:Inhibition of auto-phosphorylation of IGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349697(CHEMBL1809066)
Affinity DataIC50: 33nMAssay Description:Inhibition of auto-phosphorylation of IGFR1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349697(CHEMBL1809066)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ERG by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed