BDBM50349785 CHEMBL1809206

SMILES COc1ccn2c(cnc2c1)-c1nc(Nc2ccc(cc2OC)N2CCN(CC2)C(C)=O)ncc1Cl

InChI Key InChIKey=HQWMHIYZVJUHKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349785   

TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349785(CHEMBL1809206)
Affinity DataIC50: 8nMAssay Description:Inhibition of IGF1-induced autophosphorylation of human recombinant IGF1R expressed in mouse fibroblasts by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50349785(CHEMBL1809206)
Affinity DataIC50: 43nMAssay Description:Inhibition of IGF1-induced autophosphorylation of human recombinant IGF1R expressed in mouse fibroblasts by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed