BDBM50349987 CHEMBL1813042

SMILES CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCC(CC2)OCc2ccc(cc2)C(F)(F)F)c1C

InChI Key InChIKey=UNKLXLHKQLTRFB-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349987   

TargetSodium channel protein type 9 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50349987(CHEMBL1813042)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2012
Entry Details Article
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TargetSodium channel protein type 5 subunit alpha(Human)
Amgen

Curated by ChEMBL

LigandBDBM50349987(CHEMBL1813042)Copy SMILESCopy InChI

Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human cardiac sodium channel Nav1.5 expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2012
Entry Details Article
Copy BDB DOIPubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Amgen

Curated by ChEMBL

LigandBDBM50349987(CHEMBL1813042)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Erg expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/23/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL