BDBM50349988 CHEMBL1813050

SMILES CC(=O)Nc1cccc(Nc2ncnc(n2)N2CCC(CC2)Oc2ccc(OC(F)(F)F)cc2)c1C

InChI Key InChIKey=JFTTWRHSUYMBCX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50349988   

LigandPNGBDBM50349988(CHEMBL1813050)
Affinity DataIC50: 300nMAssay Description:Inhibition of human cardiac sodium channel Nav1.5 expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349988(CHEMBL1813050)
Affinity DataIC50: 300nMAssay Description:Inhibition of human sodium channel Nav1.7 expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50349988(CHEMBL1813050)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human Erg expressed in human HEK293 cells by patch-clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed