BDBM50350338 CHEMBL1813110
SMILES Oc1c2CN(CCn2c(=O)n1[C@H]1C[C@@H]1c1ccccc1)C(=O)Nc1ccnn1-c1cccc(Cl)c1
InChI Key InChIKey=AZAWFDKMUKHFPT-UXHICEINSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50350338
Affinity DataIC50: 8nMAssay Description:Antagonist activity at smoothened expressed in mouse Shh Light2 cells assessed as inhibition of purmorphamine- induced Gli-dependent luciferase gene ...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 20% normal human serumMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Displacement of BODIPY-cyclopamine from human Smo expressed in HEK293 cells in presence of 2% fetal calf serumMore data for this Ligand-Target Pair