BDBM50350356 CHEMBL1813279

SMILES COc1cc(ccc1OC[C@@H]1CN(C)c2ccccc2O1)C(=O)n1c(C)c(CC(O)=O)c2cc(F)ccc12

InChI Key InChIKey=OEQZRFMZVOYSAY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50350356   

TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50350356(CHEMBL1813279)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50350356(CHEMBL1813279)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed