BDBM50350363 CHEMBL1813285

SMILES Cc1c(CC(O)=O)c2ccccc2n1C(=O)c1ccc(OCC2Oc3ccccc3O2)cc1C

InChI Key InChIKey=ZTMYNGIJGRJYSF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50350363   

TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50350363(CHEMBL1813285)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at mouse DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced cAMP accumulation after 10 mins by enzyme immu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50350363(CHEMBL1813285)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]-Iloprost from human IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed