BDBM50350641 CHEMBL342357

SMILES O=C1NC(=O)c2cc(OCc3ccccc3)ccc12

InChI Key InChIKey=WPHMZNGQBMYTKD-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50350641   

TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataKi:  19nMAssay Description:Inhibition of human recombinant MAOB expressed in insect cells using kynuramine substrate using Cheng and Prusoff equation by fluorescence spectrosco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human MAO-B after 20 mins using 50 uM kynuramine as substrate by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate assessed as formation of 4-hydroxyquinoline after 20 mins by fluorescence spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant MAOB expressed in insect cells using kynuramine substrate by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataIC50: 389nMAssay Description:Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in insect cells using kynuramine substrate using Cheng and Prusoff equation by fluorescence spectrosco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in insect cells using kynuramine substrate by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataIC50: 4.17E+3nMAssay Description:Inhibition of recombinant human MAO-A after 20 mins using 50 uM kynuramine as substrate by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

LigandPNGBDBM50350641(CHEMBL342357)
Affinity DataKi:  4.67E+3nMAssay Description:For the A2a receptor binding study, the incubation contained 10 mg of the original tissue weight of the striatal membranes, 4 nM [3H]NECA, 50 nM CPA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed