BDBM50350763 CHEMBL1818445

SMILES Cc1csc(n1)C12C[C@]1(CCNC2)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KUJKCGJIUCGPED-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50350763   

TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350763(CHEMBL1818445)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP2D6 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350763(CHEMBL1818445)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP2C19 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350763(CHEMBL1818445)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP2C9 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350763(CHEMBL1818445)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP3A4 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350763(CHEMBL1818445)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP1A2 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed