BDBM50350767 CHEMBL1818543

SMILES Cc1nc(C)n(CC23C[C@]2(CCNC3)c2ccc(Cl)c(Cl)c2)n1

InChI Key InChIKey=WDNOUFVJCUYSDQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50350767   

TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350767(CHEMBL1818543)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP1A2 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350767(CHEMBL1818543)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C9 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350767(CHEMBL1818543)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C19 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350767(CHEMBL1818543)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2D6 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50350767(CHEMBL1818543)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP3A4 incubated for 10 mins before substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed