BDBM50351781 CHEMBL1823763

SMILES OC(=O)C(Cc1ccc2cc(OCc3ccccc3F)ccc2c1)NC(=O)\C=C\c1cccc(Cl)c1

InChI Key InChIKey=ZEYATNRWXGLTLA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50351781   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50351781(CHEMBL1823763)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PTP1B using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50351781(CHEMBL1823763)
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50351781(CHEMBL1823763)
Affinity DataIC50: 7.24E+3nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50351781(CHEMBL1823763)
Affinity DataIC50: 1.32E+4nMpH: 8.0Assay Description:Inhibition of human recombinant SHP1 in Tris buffer at pH 8 using OMPF as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed