BDBM50351894 CHEMBL1821789

SMILES COc1cc(Cc2nccc3cc(OC)c(OC)cc23)ccc1OCCF

InChI Key InChIKey=VIXPZCCXTICVDE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50351894   

LigandPNGBDBM50351894(CHEMBL1821789)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant PDE10A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351894(CHEMBL1821789)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of PDE3A assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50351894(CHEMBL1821789)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of PDE3B assessed as reduction in hydrolysis of [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed