BDBM50352047 CHEMBL1824015

SMILES CC(O)c1ccc(nc1)-c1ccc(Cl)c(c1)C(=O)NCCc1ccccc1Cl

InChI Key InChIKey=VNPDSQWOHMHZND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50352047   

TargetP2X purinoceptor 7(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50352047(CHEMBL1824015)
Affinity DataIC50: 668nMAssay Description:Antagonist activity at P2X7R expressed in LPS-activated human monocytes assessed as inhibition of ATP-induced IL1-beta release in presence of low ser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed