BDBM50352400 CHEMBL1823845

SMILES Clc1ccc(cc1NC(=O)N1CCC(CC1)c1nc(no1)-c1ccc2ccccc2n1)C#N

InChI Key InChIKey=ZTIRKTPQXOLPGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352400   

TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50352400(CHEMBL1823845)
Affinity DataIC50: 320nMAssay Description:Displacement of Bodipy-labelled cyclopamine from Smo expressed in COS-1 cells in presence of 2% FBS after 4 to 6 hrs by FACS flow cytometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50352400(CHEMBL1823845)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of of Bodipy-labelled cyclopamine binding to Smo expressed in COS-1 cells in presence of 20% NHS after 4 to 6 hrs by FACS flow cytometric ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed